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Human Insulin Like Growth Factor 1 (IGF1)

Researchers in California found that taller people have a higher risk of cancer. Every 10 centimeters above the average height of a tall person increases the risk of cancer by about 10 percent. More cells in taller bodies are responsible for an increased risk of cancer.
The researchers analyzed data sets from South Korea, Norway, Sweden and Austria. The study found that insulin-like growth factor 1 (igf-1) can accelerate somatic cell division and increase the chance of tumor survival. The researchers also said the risk of cancer increased by 9 percent for tall men and 12 percent for taller women. At the same time, certain types of dwarfism can greatly reduce the risk of cancer.
Studies have shown that growth promoting hormone igf-1 has a certain effect on triggering cancer.As igf-1 accelerates the rate at which cells divide during growth, it also increases the chance that cells will turn into tumors.Researchers from the university of California, riverside, calculated that the average height for men is 175 centimeters and for women is 162 centimeters.They assessed the risk of 23 types of cancer.For women, the most common types of cancer risk increase are thyroid cancer, skin cancer, lymphoma, colon cancer, ovarian cancer, breast cancer and uterine cancer.In men, it increases the risk of thyroid, skin, lymphoma, colon, kidney, biliary and central nervous system cancers. Being taller does not increase a woman's risk of esophageal, stomach, oral or cervical cancer, nor does it increase a man's risk of stomach cancer.
"Adult igf-1 hormones may directly influence cancer risk by increasing the rate of cell division," said Leonard Nunney, a professor at the research group. " this association may be responsible for the low incidence of cancer in patients with growth hormone receptor deficiency," "he added.These people with a rare form of dwarfism are known as the lenen's syndrome. The average height of women was 118 cm, and that of men was 124 cm. Their risk of cancer is usually 50 percent lower than the average person. Some cancers are not affected by height, particularly lung and cervical cancer, the California researchers said. But the problem remains.
The researchers stressed that the findings did not mean women had a higher risk of cancer. On average, men face 55 percent more risk than women. Georgina potts, health information officer at cancer research UK "There's actually a very small increase in the risk of cancer, and there are a number of things you can do to reduce the risk of cancer, like not smoking and maintaining a healthy weight," Georgina Hill, lead author of the study, said of the findings.
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